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pentobarbital will minimize the extent or outcome of prednisone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.Keep an eye on Intently (1)pentobarbital will lower the extent or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Closely. Coadministration of fentanyl with CYP